In the Pacific Northwest (PNW), winter wheat is the major dryland crop grown and it is produced in precipitation zones ranging from 16 cm to >56 cm. The PNW winter wheat production systems are characterized by sever water and wind erosion and winter annual grass weeds and plant pathogens. In 1985 and 1995 multi-interdisciplinary, large-scale, long-term integrated cropping systems studies were initiated in the high rainfall (53 cm) and low rainfall (29 cm) zones respectively. The first study known as the Integrated Pest Management (IPM) Project was conducted for 9 years until 1994 and the second study known as the Ralston Project is still being conducted. The primary focus of the studies was on conservation tillage, weed biology and management, and economics. Secondary, evaluations were on alternative cropping systems, fertilizer and herbicide inputs, soil moisture, and disease and insect populations. The nine-year IPM project (1985-1994) showed for the first time that conservation production systems were more profitable than conventional systems when weeds were adequately managed. The second study (1995-present) is examining the feasibility of no-till and conservation tillage cropping systems as a substitute or supplement to the highly erosive, weed-infested, winter wheat-fallow system. A survey of growers attending field days at the Ralston Project indicates that 61 and 51% of the growers used and adopted technologies directly from the project.