Wheat may respond to sulfur (S) fertilization, depending to a large extent on soil type. Information is needed on the influence of soil type on wheat's response to S fertilzation on alluvial and loessial soils. Field experiments were conducted on an alluvial clay (Northeast Research Station, NRS) and loessial silt loam (Macon Ridge Research Station, MRRS) to determine the influence of cultivar, S fertilizer rate, and time of S application on wheat yield. Three cultivars and four S rates, 0, 5, 10, and 20 lbs S/acre, as ammonium sulfate, were applied with spring nitrogen fertilizer. A fall rate of 20 lbs S/acre was also evaluated. There were yield differences among cultivars on both soils; however, there were no yield responses to applied S. A field experiment evaluating only spring S rates was also conducted on an alluvial sandy loam at the NRS. The sandy loam texture of this soil extended to about 20-inches deep. There was a significant yield response to spring S fertilizer rates, with yields being increased by approximately 30%. Maximum yield occurred at 10 lbs S/acre. The yield component that contributed most to the yield response was the number of spikes/acre, with applied S increasing spike number by an average of 28%. Findings indicate that S deficiencies for wheat are most likely on deep sandy soils and that the deficiency may be corrected with 10 lb S/acre, broadcast as ammonium sulfate. These experiments will continue to evaluate the influence of environment on wheat's yield response to S fertilization on different soil types.