While soil science has long played a central role in guiding manure management, societal concern over land application of manure extends well beyond the cycling of manure nutrients in soils. Livestock operators in the northeastern US face a wide range of potential complaints, from nutrient runoff and volatilization to nuisance odors. Prudent nutrient management recommendations must take into account multiple factors if they are to be adopted. We describe a multidisciplinary project aimed at supporting site-specific recommendations for manure application technologies. The project investigates the effect of alternative manure application technologies on nitrogen and phosphorus loss in surface runoff, groundwater, and air, as well as odor emissions. Project findings will be indexed to allow technology-specific evaluation of differential costs and benefits.