The magnitude of contamination, regulatory compliance and annual loadings of soils with cadmium (Cd), nickel (Ni), and lead (Pb) were determined at three sites in Tabriz where wastewater was used to irrigate vegetable gardens for at least 10 years. Heavy metal total concentrations (mg kg-1) in sandy and sandy–clay soils of pH 5.1–8.1 from all sites ranged from 0.5 to 3.4 for Cd, <0.01 to 21 for Ni, and 4 to 59 for Pb in the 0–20 cm soil depths. The concentrations had increased significantly in the gardens compared with control soils and subsoil. Annual heavy metal loading rates showed that within 5–60 years, all studied heavy metals would have exceeded their permitted limits in soils, depending on site. It was concluded that the use of wastewater in urban horticulture enriched soils with heavy metals to concentrations that may pose potential environmental and health risks in the long-term. Keywords: Wastewater; Heavy metals; Soil; Contamination; Irrigation.