Field experiments were conducted in 2005 and 2006 at the Northeast Research Station near St. Joseph, LA to evaluate the influence of row configuration, single versus twin-row, seeding and nitrogen (N) rates on yield of corn and grain sorghum. Corn trials were conducted on Commerce silt loam and grain sorghum trials on Sharkey clay. Twin-rows were centered, 24-cm apart, on raised 102-cm wide beds. For corn, seeding rates of 61,750, 74,100, 86,450, and 98,800 seed ha-1 and N rates of 168, 202, 235, and 268 kg ha-1 were evaluated. Seeding rates of 20 and 26 seed m-1 and 10 and 13 seed m-1 for single and twin-rows, respectively, and N rates of 101, 134 and 168 kg ha-1 were evaluated for grain sorghum. There were no statisticaliy significant effects of row configuration on corn grain yield in 2005 or 2006. Average grain yields were 12, 150 kg ha-1 on single rows and 12,220 kg ha-1 on twin rows in 2005 and 8,000 kg ha-1 on single rows and 8,280 kg ha-1 on twin rows in 2006. Seeding and N rates affected grain yields similarly for each row configuration. Averaged over row configuration and N rate treatments, optimum seeding rate was 74,100 seed ha-1 each year, 77,110 plants ha-1 in 2005 and 72,220 plants ha-1 in 2006. Averaged over row configuration and seeding rate, optimum N rate each year was between 202 and 235 kg ha-1. For grain sorghum, grain yields in both 2005 and 2006 were significantly higher for the twin-row configuration. Grain yields on twin rows compared to single rows were increased 6.6% in 2005 and 5.8% in 2006. Irrigation, seeding rate and N rate treatments had little affect on grain yield.